Multisystem Inflammatory Syndrome in Children (MIS-C)

Last Updated: December 2022

Boston Children’s Hospital (BCH) describes Multisystem Inflammatory Syndrome in Children—also called MIS-C or pediatric multi-system inflammatory syndrome temporarily related to SARS CoV-2, PMIS or PIMS-TS)—as a potentially serious illness in children that appears to be a delayed, post-infectious complication of a COVID-19 infection. 

The hospital explains that MIS-C has varied symptoms that affect several organs and systems in the body. Many children have symptoms resembling toxic shock syndrome or Kawasaki disease, in which the coronary arteries enlarge or form aneurysms. Also common are heart inflammation with impaired heart function and low blood pressure, rash or red eyes, and gastrointestinal symptoms.Symptoms can occur in different combinations. The Centers for Disease Control and Prevention share that symptoms may include an ongoing fever PLUS more than one of the following:  stomach pain, bloodshot eyes, diarrhea, dizziness or lightheadedness (signs of low blood pressure), skin rash, and vomiting.  The CDC cautions that not all children will have all the same symptoms (Source).

BCH officials recommend consulting with your primary care provider or seeking Emergency Department care if you think your child has symptoms of MIS-C. Blood tests may be recommended, depending on your child’s symptoms. Children with MIS-C  need close observation by pediatric specialists in rheumatology, cardiology, critical care, and sometimes hematologists and infectious disease doctors. (Source)  

Related Resources:

COVID-19 in Children

COVID-19 en niños